The article deals with history of emergence of marine tourism in the South East of Russian Federation.It analyzes contemporary approaches to arrangement of marine tourism, defines the priority kinds of sea Laptop Bag holidays, emphasizes problems of cruise carriages and outlines the main trends in the development of marine tourism.Keywords: marine
Aims: Leptin plays an important role in the pathogenesis of obesity and diabetes, yet the regulatory mechanisms of this hormone have not been fully elucidated.In this study, we aimed to clarify the roles of insulin and glucose in leptin secretion and mRNA production using inhibitors of insulin signal transduction in adipocytes cultured under glucos
Over the last several decades, transportation scientists have made substantial progress in identifying and tackling transport-related problems by elaborating sophisticated policy instruments.Originally, the policy instruments were developed and designed to tackle inefficiencies caused by conventional (human-driven) vehicles.However, questions remai
Background Adaptive cellular therapy (ACT), particularly chimeric antigen receptor (CAR)-T cell therapy, has been successful in the treatment of hemopoietic malignancies.However, poor trafficking of administered effector T cells to the tumor poses a great hurdle for this otherwise powerful therapeutic approach in solid cancers.Our previous study re